Both laboratory and synchrotron radiation x-ray tomography (SR-XRT) are viable for in-situ experiments. The x-ray brightness from tube source is about ten orders magnitude less than that from synchrotron radiation. The setup for an in-situ experiment using LB-XRT has to be considered beforehand. Micrometer sized voids as defects pre-existing in alloys during processing might affect mechanical performance in service. For the in-situ study of these micro-voids, the samples in millimeter size can be much more easily prepared and manipulated than those in hundreds or tens of micrometers. In consequence, the energy needs to reach one hundred keV with polychromatic X-ray tube source, especially for alloys contain heavy elements. The imaging resolution and the field of view have also to be considered for the study of the voids morphology evolvement. The temporal resolution of LB-XRT must be in the same time scale so that the structure can keep stable when the specified condition is applied .